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Winterschool 2010

On Biomolecular Solid-State NMR

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Home Program
Program
  1. Lectures, problem solving sessions, and workshops will take place in the Mansfield Ballroom (location M), located in the Toll House Conference Center behind the Inn. Electrical outlets and wireless internet access will be provided in the Mansfield Ballroom. Attendees should bring their own laptops to download lecture materials and problem sets for the workshop.
  2. Buffet-style breakfast will be served in the Spruce Room, adjacent to the Mansfield Ballroom. Buffet-style dinners will be served in the H.H. Bingham Room (location H), on the lower level of the main building of the Inn. Lunch may be available in the Inn, but is not provided by the Winter School.
  3. Attendees will receive room assignments at the registration desk, located in the main building of the Inn. Rooms will be either in the Inn itself or in nearby condominiums within walking distance of the Inn.
The Stowe Mountain Road Shuttle provides free transportation along Mountain Road, connecting the Inn, the village of Stow and the Mt. Mansfield ski area. Shuttle buses are available every 30 minutes.
 
The complete program is available as a pdf for download.
 

Lecture Materials

Lecture material available as compressed archives (zip)

  1. All lecture notes
  2. CAD design of a low-temperature probe for DNP-enhanced MAS NMR (Alexander Barnes)
  3. Matlab package for DNP simulations without Relaxation (Thorsten Maly)
  4. Workshop material for computational structure determination of non-trivial proteins (fRienstra group)
 

Sunday, January 24th

 Time

Speaker

Title

Location

2.00p-

9:00p

 

Registration

 

7:00p-

8:00p

 

Reception/Dinner

H

8:00p-

8:15p

Bob Griffin

Rob Tycko

Opening Remarks

M

8:30p-

9:30p

Hartmut Oschkinat

The role of solid state NMR in biological sciences: perspectives from Europe

Download Oschkinat Lecture 1

M

 

Monday, January 25th

 Time

Speaker

Title

Location

7.00a-

8:00a

 

Breakfast

M

8:00a-

9:30a

Rob Tycko

Basic principles of solid-state NMR, pulse sequences and structural measurements

Download Tycko Lecture 1

M

 

9:30a-

10:00a

 

Coffee break

M

10:00-

11:30a

Chris Jaroniec

Heteronuclear recoupling and decoupling under MAS

Download Jaroniec Lectures 1 and 2

M

11:30-

2:00p

 Lunch
 

3:00p-

4:30p

Hartmut Oschkinat

Isotopic labeling etc.

Download Oschkinat Lecture 2

 M

5:00p-

6:30p

Rob Tycko

Chris Jaroniec

Heteronuclear recoupling; tensor alignment methods

Download Tycko Lecture 2

Download Tycko Recoupling Notes

M

6:30p-

7:30p

 Buffet dinner
H

7:30p-

9:00p

Chad Rienstra

Resonance assignment and structure determination for high-molecular weight solid proteins

Download Rienstra Lecture 1

M

 9:00p-

11:00

  Fireside Tavern
 

 

 

Tuesday, January 26th

 Time

Speaker

Title

Location

7.00a-

8:00a

 

Breakfast

M

8:00a-

9:30a

Mei Hong

Theory and techniques for studies of molecular dynamics

Download Hong Lecture 1

M

 

9:30a-

10:00a

 

Coffee break

M

10:00-

11:30a

Bob Griffin

Dynamic Nuclear Polarization I

Download Griffin Lecture 1

M

11:30a-

5:00p

 Free time
 

4:30p-

6:30p

Rob Tycko

Problem solving session

Download Tycko Problem Set 1

M

6:30p-

7:30p

 Buffet dinner
H

7:30p-

9:00p

Shimon Vega

Floquet Theory and proton NMR under MAS

Download Vega Lecture 1

Download Vega Lecture 2

Download Vega Lecture 3

M

9:30p-

10:30p

Alexander Barnes

CAD Design of MAS NMR Instrumentation Further instructions can be found here: Workshop instrumentation design

Download Barnes Lecture 1

M

 10:30p-

 11:30p

 Fireside Tavern
 
 

Wednesday, January 27th

 Time

Speaker

Title

Location

7.00a-

8:00a

 

Breakfast

M

8:00a-

9:30a

Ann McDermott

Effects of Intermediate Exchange Dynamics on NMR Spectra

Download McDermott Lecture 1 (Updated, 01/27/10)

M

 

9:30a-

10:00a

 

Coffee break

M

10:00-

11:30a

Thorsten Maly

Dynamic Nuclear Polarization II

Download Maly Lecture 1

Download Maly Additional Notes

Download Maly Matlab Scripts (Updated, 01/26/10)

M

11:30a-

2:00p

 Free time
 

2:00p-

5:00p

Chad Rienstra

Workshop on computational structure determination for non-trivial proteins. Further information and software download instructions: Computational Structure Determination.

Download Rienstra Workshop Material

M

5:00p-

6:30p

Shimon Vega

Dynamic Nuclear Polarization III

Download Vega Lecture 4

Download Vega Lecture 5

M

6:30p-

7:30p

 Buffet dinner
H

7:30p-

9:00p

Mei Hong

MAS NMR of phospholipids and membrane boundsystems

Download Hong Lecture 2 (Udated, 01/27/10)

M

9:15p-

10:00p

 

DNP problem session/discussion

Download Griffin DNP Notes 1

Download Griffin DNP Notes 2

Download Griffin DNP Notes 3

M

 10:00p-

11:30p

  Fireside Tavern
 
 

Thursday, January 28th

 Time

Speaker

Title

Location

7.00a-

8:00a

 

Breakfast

M

8:00a-

9:30a

Stan Opella

Oriented Systems I

Download Opella Lecture 1

M

 

9:30a-

10:00a

 

Coffee break

M

10:00-

11:30a

Tim Cross

Oriented Systems II

Download Cross Lecture 1

M

11:30a-

2:00p

 Free time
 

2:00p-

5:00p

Alexander Barnes

Stan Opella

Kent Thurber (NIH)

John Stringer (Varian)

Michael Fey (Bruker)

New developments in instrumentation for biomolecluar solid-state NMR.

Workshop: Instrumentation Design

Download Barnes Lecture 2 

Download Thurber Lecture 1

Download Stringer Lecture 1

Download Fey Lecture 1

Download Opella Lecture 2

M

5:00p-

6:30p

Tim Cross

Stan Opella

Membrane protein production and labeling

Download Cross Lecture 2

Download Opella Lecture 3

M

6:30p-

9:30p

 Winter school banquet (Transportation discussed later)
J

 9:30p-

11:00p

  Fireside Tavern
 
 
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